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US09221767B2 Substituted phthalazinones as rock inhibitors 有权
取代的2,3-二氮杂萘酮作为岩石抑制剂

Substituted phthalazinones as rock inhibitors
Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
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