Invention Grant
US09221819B2 Spirocyclic compounds as modulators of chemokine receptor activity
有权
螺环化合物作为趋化因子受体活性的调节剂
- Patent Title: Spirocyclic compounds as modulators of chemokine receptor activity
- Patent Title (中): 螺环化合物作为趋化因子受体活性的调节剂
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Application No.: US14503456Application Date: 2014-10-01
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Publication No.: US09221819B2Publication Date: 2015-12-29
- Inventor: T. G. Murali Dhar , John V. Duncia , Daniel S. Gardner , Weiwei Guo , John Hynes
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- Main IPC: C07D471/10
- IPC: C07D471/10 ; A61K31/4427 ; C07D401/12 ; C07D405/12 ; C07D413/12 ; C07D471/04
Abstract:
The present application describes modulators of chemokine receptor activity of formula I or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.
Public/Granted literature
- US20150018347A1 SPIROCYCLIC COMPOUNDS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Public/Granted day:2015-01-15
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