Invention Grant
US09222113B2 Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
有权
用于共生产1,4-丁二醇和γ-丁内酯的微生物和方法
- Patent Title: Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
- Patent Title (中): 用于共生产1,4-丁二醇和γ-丁内酯的微生物和方法
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Application No.: US13936878Application Date: 2013-07-08
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Publication No.: US09222113B2Publication Date: 2015-12-29
- Inventor: Jun Sun , Mark J. Burk , Anthony P. Burgard , Robin E. Osterhout , Wei Niu , John D. Trawick , Robert Haselbeck
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Main IPC: C12P7/18
- IPC: C12P7/18 ; C12P17/04 ; C12N1/20
Abstract:
The invention provides non-naturally occurring microbial organisms comprising 1,4-butanediol (14-BDO) and gamma-butyrolactone (GBL) pathways comprising at least one exogenous nucleic acid encoding a 14-BDO and GBL pathway enzyme expressed in a sufficient amount to produce 14-BDO and GBL. The invention additionally provides methods of using such microbial organisms to produce 14-BDO and GBL.
Public/Granted literature
- US20140162327A1 MICROORGANISMS AND METHODS FOR THE COPRODUCTION 1,4-BUTANEDIOL AND GAMMA-BUTYROLACTONE Public/Granted day:2014-06-12
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