Methods, apparatus, systems and articles of manufacture are disclosed to validate translated guest code in a dynamic binary translator. An example apparatus disclosed herein includes a translator to generate a first translation of code to execute on a host machine, the first translation of the guest code to facilitate creating a first translated guest code, and the translator to generate a second translation of the translated guest code to execute on the host machine. The example apparatus also includes a translation versions manager to identify a first host machine state based on executing a portion of the first translation, and the translation versions manager to identify a second host machine state based on executing a portion of the second translation. The example system also includes a validator to determine a state divergence status of the second translation based on a comparison between the first host machine state and the second host machine state.