Invention Grant
- Patent Title: Compounds that are ERK inhibitors
- Patent Title (中): ERK抑制剂的化合物
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Application No.: US14431485Application Date: 2013-09-26
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Publication No.: US09226922B2Publication Date: 2016-01-05
- Inventor: Kevin J. Wilson , David J. Witter , Matthew H. Daniels , Angie R. Angeles , Phieng Siliphaivanh , David Sloman , Brendan O'Boyle , Danielle Falcone , Catherine White , Ron Ferguson , Wei Zhou , Kathryn Lipford , Umar Faruk Mansoor , Salem Fevrier , Xianhai Huang , Ravi Kurukulasuriya , Judson E. Richard , Shuyi Tang , Christopher Boyce , Joseph Kozlowski , Raman Kumar Bakshi , Ganesh Babu Karunakaran
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Richard S. Parr; Laura M. Ginkel
- International Application: PCT/US2013/061884 WO 20130926
- International Announcement: WO2014/052566 WO 20140403
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/437 ; C07D471/04 ; A61K45/06 ; A61K31/4545

Abstract:
Disclosed are the ERK inhibitors of formula (1.0), having a pyrazolopyridine base structure, and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0).
Public/Granted literature
- US20150258074A1 NOVEL COMPOUNDS THAT ARE ERK INHIBITORS Public/Granted day:2015-09-17
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