Invention Grant
US09227955B2 Compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same
有权
具有血管发生抑制活性的化合物，其制备方法和包含其的药物组合物
- Patent Title: Compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same
- Patent Title (中): 具有血管发生抑制活性的化合物，其制备方法和包含其的药物组合物
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Application No.: US14235439Application Date: 2012-07-27
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Publication No.: US09227955B2Publication Date: 2016-01-05
- Inventor: Ji Han Kim , Je Hak Kim , Joon Kwang Lee , Hahn-Sun Jung , Nam Seok Han , Yong Park , Seung-Hoon Kang , Hee Jin Jeong , Kyung-Tae Lee , Hye Eun Choi , Yong Ha Chi , Joo Han Lee , Soo Heui Paik
- Applicant: Ji Han Kim , Je Hak Kim , Joon Kwang Lee , Hahn-Sun Jung , Nam Seok Han , Yong Park , Seung-Hoon Kang , Hee Jin Jeong , Kyung-Tae Lee , Hye Eun Choi , Yong Ha Chi , Joo Han Lee , Soo Heui Paik
- Applicant Address: KR Seoul
- Assignee: Boryung Pharmaceutical Co., Ltd.
- Current Assignee: Boryung Pharmaceutical Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Sterne, Kessler, Goldstein & Fox PLLC
- Priority: KR10-2011-0074638 20110727
- International Application: PCT/KR2012/006037 WO 20120727
- International Announcement: WO2013/015657 WO 20130131
- Main IPC: C07D213/02
- IPC: C07D213/02 ; C07D401/12 ; C07D401/14 ; C07D213/82 ; C07D495/04 ; C07D413/14 ; C07D417/14
Abstract:
Disclosed are an anti-angiogenic compound, represented by Chemical Formula I, or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutically acceptable composition including the same. Because the compound of Chemical Formula I potently suppresses the angiogenesis, the compound of Chemical Formula I is applicable to the prevention and treatment of diseases caused by aberrant activity of vascular endothelial growth factor, and available as an anti-angiogenic agent.
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