Invention Grant
US09229005B2 Compositions and methods for in vitro diagnostic tests including sulfonic acid compound
有权
用于体外诊断试验的组合物和方法,包括磺酸化合物
- Patent Title: Compositions and methods for in vitro diagnostic tests including sulfonic acid compound
- Patent Title (中): 用于体外诊断试验的组合物和方法,包括磺酸化合物
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Application No.: US13849056Application Date: 2013-03-22
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Publication No.: US09229005B2Publication Date: 2016-01-05
- Inventor: Gary Opperman , Wendy Nelson
- Applicant: SurModics, Inc.
- Applicant Address: US MN Eden Prairie
- Assignee: SURMODICS IVD, INC.
- Current Assignee: SURMODICS IVD, INC.
- Current Assignee Address: US MN Eden Prairie
- Agency: Kagan Binder, PLLC
- Main IPC: G01N21/78
- IPC: G01N21/78 ; C12Q1/28 ; G01N33/58 ; G01N33/52 ; G01N33/535 ; G01N33/558

Abstract:
The invention provides compositions, kits, and methods for performing colorimetric analysis. A substrate is reacted to generate a chromogenic reaction product, and a reaction stop reagent that is a sulfonic acid is added to stop and stabilize the reaction product. The absorbance properties of the chromogenic reaction product can be maintained over significantly longer periods of time of that of conventional reagents and methods. The sulfonic acid can be used in assays such as ELISAs in order to provide a more accurate and safer detection of analytes in a biological sample.
Public/Granted literature
- US20130252261A1 COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING SULFONIC ACID COMPOUND Public/Granted day:2013-09-26
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