Invention Grant
- Patent Title: Inhibition of WDR5 interaction with its binding partners
- Patent Title (中): 抑制WDR5与其结合配偶体的相互作用
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Application No.: US13160086Application Date: 2011-06-14
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Publication No.: US09233086B2Publication Date: 2016-01-12
- Inventor: Shaomeng Wang , Hacer Karatas , Yali Dou , Elizabeth Townsend , Denzil Bernard
- Applicant: Shaomeng Wang , Hacer Karatas , Yali Dou , Elizabeth Townsend , Denzil Bernard
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K31/155
- IPC: A61K31/155 ; A61K31/166 ; A61K31/16 ; A61K31/165 ; A61K31/167 ; A61K31/4164 ; A61K31/445
Abstract:
Peptidomimetics that inhibit the interaction between MLL1 and WDR5 are disclosed. Methods of inhibiting MLL1 activity and methods of treating cancers also are disclosed.
Public/Granted literature
- US20110312997A1 Inhibition of WDR5 Interaction with Its Binding Partners Public/Granted day:2011-12-22
Information query
