Invention Grant
- Patent Title: Proteasome inhibitors and methods of using the same
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Application No.: US13949346Application Date: 2013-07-24
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Publication No.: US09233115B2Publication Date: 2016-01-12
- Inventor: Raffaella Bernardini , Alberto Bernareggi , Paolo G. Cassara , Sankar Chatterjee , Germano D'Arasmo , Sergio De Munari , Edmondo Ferretti , Mohamed Iqbal , Ernesto Menta , Patricia A. Messina McLaughlin , Ambrogio Oliva
- Applicant: Cephalon, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals Inc.
- Current Assignee: Millennium Pharmaceuticals Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Baker & Hostetler LLP
- Main IPC: A61K31/69
- IPC: A61K31/69 ; A61K45/06 ; C07F5/02
Abstract:
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Public/Granted literature
- US20140088042A1 Proteasome Inhibitors And Methods Of Using The Same Public/Granted day:2014-03-27
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