发明授权
- 专利标题： Purification method of azacyclohexapeptide or its salt
- 专利标题（中）： 氮杂环己肽或其盐的纯化方法
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申请号： US13640836申请日： 2011-04-15
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公开(公告)号： US09233318B2公开(公告)日： 2016-01-12
- 发明人: Zhonghao Zhuo , Zhijun Tang , Tianhui Xu , Ming Li , Xiaoming Ji , Xiaoliang Gao
- 申请人： Zhonghao Zhuo , Zhijun Tang , Tianhui Xu , Ming Li , Xiaoming Ji , Xiaoliang Gao
- 申请人地址： CN Shanghai
- 专利权人： SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD.
- 当前专利权人： SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD.
- 当前专利权人地址： CN Shanghai
- 代理机构： McClure, Qualey & Rodack, LLP
- 优先权： CN201010147002 20100415
- 国际申请： PCT/CN2011/072833 WO 20110415
- 国际公布： WO2011/127835 WO 20111020
- 主分类号： C07K1/14
- IPC分类号： C07K1/14 ; C07K1/16 ; C07K1/22 ; C07K7/50 ; B01D15/26 ; B01D15/08 ; B01D15/42 ; C07K7/54 ; C07K1/20 ; C07K7/56
摘要：
A purification method of the compound represented by formula 1 is provided, which includes the following steps: (1) loading crude compound 1 on macroporous adsorbent resin, (2) washing the macroporous adsorbent resin with an aqueous solution, an organic solvent or a mixture solution of organic solvent and water, (3) eluting with an aqueous solution, an organic solvent or a mixture solution of organic solvent and water. The purified compound represented by formula 1 is obtained.
公开/授权文献
- US20130030150A1 Purification Method of Azacyclohexapeptide or Its Salt 公开/授权日：2013-01-31