发明授权
- 专利标题： Transport protein which is used to introduce chemical compounds into nerve cells
- 专利标题（中）： 用于将化学物质引入神经细胞的运输蛋白
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申请号： US13608631申请日： 2012-09-10
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公开(公告)号： US09234011B2公开(公告)日： 2016-01-12
- 发明人: Andreas Rummel
- 申请人： Andreas Rummel
- 申请人地址： GB Abingdon, Oxfordshire
- 专利权人： Ipsen Bioinnovation Limited
- 当前专利权人： Ipsen Bioinnovation Limited
- 当前专利权人地址： GB Abingdon, Oxfordshire
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Jin Wang, Esq.
- 优先权： DE102004043009 20040906
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/33 ; A61K47/48 ; A61K8/66 ; A61K38/48 ; A61Q19/08
摘要：
The invention relates to a transport protein which can be obtained by modifying the heavy chain of the neurotoxin formed by Clostridium botulinum. The protein binds specifically to nerve cells with a higher affinity as the native neurotoxin. The invention also relates to a method for the production of transport protein, the nucleic acids coding for the transport protein, the transport protein containing pharmaceutical and cosmetic compositions and use thereof.
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