Invention Grant
- Patent Title: Cyclic peptide and conjugate thereof for binding to keratinocytes
- Patent Title (中): 环肽和结合物用于结合角质形成细胞
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Application No.: US14000811Application Date: 2012-02-21
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Publication No.: US09238056B2Publication Date: 2016-01-19
- Inventor: Nina Østergaard Knudsen , Thorsten Thormann
- Applicant: Nina Østergaard Knudsen , Thorsten Thormann
- Applicant Address: DK Ballerup
- Assignee: LEO PHARMA A/S
- Current Assignee: LEO PHARMA A/S
- Current Assignee Address: DK Ballerup
- Agency: Birch Stewart Kolasch & Birch, LLP
- International Application: PCT/EP2012/052955 WO 20120221
- International Announcement: WO2012/113803 WO 20120830
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K31/593 ; A61K8/64 ; A61K38/12 ; A61K47/48 ; C07K7/06 ; C07K7/64 ; A61K9/127 ; A61K31/047 ; A61K38/00
Abstract:
A cyclic peptide capable of binding specifically to the α2 I domain of a collagen binding integrin receptor may be conjugated to a drug containing particle via a linker moiety. The conjugate may be used to target a therapeutic drug to a cell expressing a collagen binding integrin receptor on its surface.
Public/Granted literature
- US20140023700A1 CYCLIC PEPTIDE AND CONJUGATE THEREOF FOR BINDING TO KERATINOCYTES Public/Granted day:2014-01-23
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