The disclosure relates to a security zipper and bag, or one-time closable zipper and bag, and methods of manufacture thereof, wherein the zipper includes double zipper profiles with a layer or strip of adhesive positioned between the two interlocking elements of one of the zipper profiles. Upon the one-time closing of the zipper, the adhesive secures the two double zipper profiles together and prevents a subsequent opening of the zipper or bag without leaving evidence of such opening, such as damage to the zipper or bag. Alternately, adhesive can be provided within the female profiles, with a liner over the adhesive to prevent premature activation.