Invention Grant
US09249096B2 Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
有权
吡咯烷酮甲酰胺化合物可用作内皮脂肪酶抑制剂
- Patent Title: Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
- Patent Title (中): 吡咯烷酮甲酰胺化合物可用作内皮脂肪酶抑制剂
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Application No.: US14346747Application Date: 2012-09-26
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Publication No.: US09249096B2Publication Date: 2016-02-02
- Inventor: Lynn Abell , Leonard Adam , Cullen L. Cavallaro , Heather Finlay , Todd J. Friends , Jon J. Hangeland , Ji Jiang , R. Michael Lawrence , Jennifer X. Qiao , Carol Hui Hu , Tammy C. Wang
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Barry H. Jacobsen
- International Application: PCT/US2012/057180 WO 20120926
- International Announcement: WO2013/049096 WO 20130404
- Main IPC: C07D207/38
- IPC: C07D207/38 ; C07D403/12 ; C07D401/12 ; C07D207/277 ; C07D401/06 ; C07D405/04 ; C07D405/06 ; C07D409/04 ; C07D417/04 ; C07D417/06 ; C07D207/28 ; C07D233/61 ; C07D413/06
Abstract:
The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments. The disclosure also provides a novel method of treating diseases or conditions related to the activity of endothelial lipase by use of compounds according to Formula (II): as defined in the specification and compositions comprising any of the compounds.
Public/Granted literature
- US20140213588A1 PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS Public/Granted day:2014-07-31
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