Invention Grant
US09249153B2 Pharmaceutical composition for treating aging-associated diseases, containing progerin expression inhibitor as active ingredient, and screening method of said progerin expression inhibitor
有权
用于治疗老化相关疾病的药物组合物，含有progerin表达抑制剂作为活性成分，以及所述progerin表达抑制剂的筛选方法
- Patent Title: Pharmaceutical composition for treating aging-associated diseases, containing progerin expression inhibitor as active ingredient, and screening method of said progerin expression inhibitor
- Patent Title (中): 用于治疗老化相关疾病的药物组合物，含有progerin表达抑制剂作为活性成分，以及所述progerin表达抑制剂的筛选方法
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Application No.: US14005558Application Date: 2012-03-19
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Publication No.: US09249153B2Publication Date: 2016-02-02
- Inventor: Bum Joon Park , Nam Chul Ha , Gyu Yong Song , Ji Hyun Lee , Su Jin Lee , Youn Sang Jung
- Applicant: Bum Joon Park , Nam Chul Ha , Gyu Yong Song , Ji Hyun Lee , Su Jin Lee , Youn Sang Jung
- Applicant Address: KR Busan KR Daejeon
- Assignee: PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION,THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY
- Current Assignee: PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION,THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY
- Current Assignee Address: KR Busan KR Daejeon
- Agency: Revolution IP, PLLC
- Priority: KR10-2011-0024308 20110318; KR10-2012-0027028 20120316
- International Application: PCT/KR2012/001953 WO 20120319
- International Announcement: WO2012/128521 WO 20120927
- Main IPC: A61K31/352
- IPC: A61K31/352 ; C07D493/04 ; A61K31/70 ; A61K31/7088 ; G01N33/50 ; A61K31/713
Abstract:
Disclosed are a method for treating an aging-related disease and a method for screening a therapeutic agent for an aging-related disease. The method for treating an aging-related disease includes administering to a subject a progerin expression inhibitor as an active ingredient. The method for screening a therapeutic agent for an aging-related disease includes selecting a candidate drug inhibitory of progerin expression.
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