Invention Grant
- Patent Title: Anti-IL-18 antibodies and their uses
- Patent Title (中): 抗IL-18抗体及其用途
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Application No.: US13993537Application Date: 2011-12-20
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Publication No.: US09255144B2Publication Date: 2016-02-09
- Inventor: Claire Dobson , Steven Lane , Philip Newton , Martin Schwickart , Ann-Charlott Steffen
- Applicant: Claire Dobson , Steven Lane , Philip Newton , Martin Schwickart , Ann-Charlott Steffen
- Applicant Address: GB Cambridge
- Assignee: MedImmune Limited
- Current Assignee: MedImmune Limited
- Current Assignee Address: GB Cambridge
- International Application: PCT/EP2011/073496 WO 20111220
- International Announcement: WO2012/085015 WO 20120628
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/00 ; C07K16/24
Abstract:
The present invention provides human, humanized and/or chimeric antibodies as well as fragments, derivatives/conjugates and compositions thereof with a specific binding affinity for interleukin-18. The invention includes the use of these antibodies for diagnosing and treating diseases associated with increased IL-18 activity, the latter in the form of a pharmaceutical composition.
Public/Granted literature
- US20140004128A1 ANTI-IL-18 ANTIBODIES AND THEIR USES Public/Granted day:2014-01-02
Information query
