Invention Grant
US09261626B2 Contact lenses with enzymatically degradable coatings thereon 有权
具有可降解酶层的隐形眼镜

  • Patent Title: Contact lenses with enzymatically degradable coatings thereon
  • Patent Title (中): 具有可降解酶层的隐形眼镜
  • Application No.: US13706737
    Application Date: 2012-12-06
  • Publication No.: US09261626B2
    Publication Date: 2016-02-16
  • Inventor: Newton T. SamuelNirupama Kenkare
  • Applicant: Novartis AG
  • Applicant Address: CH Basel
  • Assignee: Novartis AG
  • Current Assignee: Novartis AG
  • Current Assignee Address: CH Basel
  • Agent Jian Zhou
  • Main IPC: G02B1/04
  • IPC: G02B1/04
Contact lenses with enzymatically degradable coatings thereon
Abstract:
The invention is related to a disposable contact lens comprising a top coating which is made of a hydrophilic polymeric material including dangling hydrophilic polymer chains covalently linked to the hydrophilic polymeric material through oligo-caprolactone linkages susceptible to enzymatic degradation in the eyes. The top coating is stable to lens processing/storage and confers lubricity to the lens. However, it slowly is degraded during the lens wear due to the action of enzymes (e.g., Lipase) in tear film. The loss in lubricity will be experienced as a drop in comfort for the lens wearer and thereby serves as the built-in compliance features of the disposable contact lens.
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