Generally, this disclosure relates to adaptive interrupt moderation. A method may include determining, by a host device, a number of connections between the host device and one or more link partners based, at least in part, on a connection identifier associated with each connection; determining, by the host device, a new interrupt rate based at least in part on a number of connections; updating, by the host device, an interrupt moderation timer with a value related to the new interrupt rate; and configuring the interrupt moderation timer to allow interrupts to occur at the new interrupt rate.