Invention Grant
US09273054B2 Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors
有权
取代的嘧啶并[1,6-a]嘧啶作为Lp-PLA2抑制剂
![Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors](/docs/US/2016-03-01/US09273054B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors
- Patent Title (中): 取代的嘧啶并[1,6-a]嘧啶作为Lp-PLA2抑制剂
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Application No.: US14234687Application Date: 2012-07-25
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Publication No.: US09273054B2Publication Date: 2016-03-01
- Inventor: Zehong Wan , Kai Long , Xiaomin Zhang , Haihua Yu
- Applicant: Zehong Wan , Kai Long , Xiaomin Zhang , Haihua Yu
- Applicant Address: GB Brentford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Fang Qian; William R. Majarian
- Priority: WOPCT/CN2011/077702 20110727
- International Application: PCT/EP2012/064598 WO 20120725
- International Announcement: WO2013/014185 WO 20130131
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D239/70 ; C07D487/04
![Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors](/abs-image/US/2016/03/01/US09273054B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
Public/Granted literature
- US20140179716A1 BICYCLIC PYRIMIDONE COMPOUNDS Public/Granted day:2014-06-26
Information query
IPC分类:
