Invention Grant
- Patent Title: Methods for producing secreted polypeptides having biological activity
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Application No.: US14081340Application Date: 2013-11-15
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Publication No.: US09273104B2Publication Date: 2016-03-01
- Inventor: Mads Bjornvad , Debbie Yaver
- Applicant: Novozymes A/S , Novozymes, Inc.
- Applicant Address: US CA Davis DK Bagsvaerd
- Assignee: NOVOZYMES, INC.,NOVOZYMES A/S
- Current Assignee: NOVOZYMES, INC.,NOVOZYMES A/S
- Current Assignee Address: US CA Davis DK Bagsvaerd
- Agent Robert Starnes
- Main IPC: C07K7/00
- IPC: C07K7/00 ; C12N9/20 ; C07K14/37 ; C12N15/62 ; C12N15/81 ; C12P21/02 ; A61K38/00
Abstract:
The present invention relates to methods for producing a polypeptide having biological activity, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first polynucleotide encoding the polypeptide operably linked to a second polynucleotide encoding a variant signal peptide or a variant prepropeptide; and (b) isolating the secreted polypeptide having biological activity from the cultivation medium.
Public/Granted literature
- US20140142278A1 Methods For Producing Secreted Polypeptides Having Biological Activity Public/Granted day:2014-05-22
Information query
