According to one embodiment, a method for exchanging data in a system that includes a main processor in communication with an active memory device is provided. The method includes a processing element in the active memory device receiving an instruction from the main processor and receiving a store request from a thread running on the main processor, the store request specifying a memory address associated with the processing element. The method also includes storing a value provided in the store request in a queue in the processing element and the processing element performing the instruction using the value from the queue.