Invention Grant
- Patent Title: Analogs of sodium channel peptide toxin
- Patent Title (中): 钠通道肽毒素的类似物
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Application No.: US13808504Application Date: 2011-07-07
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Publication No.: US09279003B2Publication Date: 2016-03-08
- Inventor: Jae Hyun Park , Donald J. Kyle
- Applicant: Jae Hyun Park , Donald J. Kyle
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Purdue Pharma L.P.
- Agent Alan L. Koller; Weiying Yang
- International Application: PCT/IB2011/001631 WO 20110707
- International Announcement: WO2012/004664 WO 20120112
- Main IPC: C07K14/435
- IPC: C07K14/435 ; A61K38/00
Abstract:
The present invention relates to a peptide and its analogs that selectively inhibit the Nav1.7 sodium channel. The present invention also relates to pharmaceutical compositions useful for treating or preventing a disorder responsive to the blockade of sodium ion channels, especially Nav1.7 sodium ion channels. The present invention further provides methods of treating a disorder responsive to the blockade of sodium channels, and particularly Nav1.7 sodium channels, in a mammal suffering from excess activity of the channels, compositions and methods for providing analgesia by administering a peptide of the invention.
Public/Granted literature
- US20130296247A1 Analogs of Sodium Channel Peptide Toxin Public/Granted day:2013-11-07
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