发明授权
- 专利标题: Pyrazolyl-pyrimidine derivatives as kinase inhibitors
- 专利标题(中): 吡唑基 - 嘧啶衍生物作为激酶抑制剂
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申请号: US14110596申请日: 2012-04-03
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公开(公告)号: US09284298B2公开(公告)日: 2016-03-15
- 发明人: Francesco Casuscelli , Maria Gabriella Brasca , Marina Caldarelli , Giovanni Cervi , Teresa Disingrini , Francesca Quartieri
- 申请人: Francesco Casuscelli , Maria Gabriella Brasca , Marina Caldarelli , Giovanni Cervi , Teresa Disingrini , Francesca Quartieri
- 申请人地址: IT Nerviano (MI)
- 专利权人: NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人: NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人地址: IT Nerviano (MI)
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 优先权: EP11161925 20110411
- 国际申请: PCT/EP2012/056047 WO 20120403
- 国际公布: WO2012/139930 WO 20121018
- 主分类号: A61K45/06
- IPC分类号: A61K45/06 ; A61K31/506 ; C07D403/04 ; C07D401/14 ; C07D403/14 ; C07D413/14
摘要:
The present invention relates to pyrazolyl-pyrimidine derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.
公开/授权文献
- US20140051708A1 PYRAZOLYL-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS 公开/授权日:2014-02-20
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