- 专利标题： (R)-Nifuratel, its use for the treatment of infections and synthesis of (R) and (S)-Nifuratel
-
申请号： US14400071申请日： 2013-03-13
-
公开(公告)号： US09284306B2公开(公告)日： 2016-03-15
- 发明人: Stefania Gagliardi , Alessandra Consonni , Federico Mailland , Anna Bulgheroni
- 申请人： POLICHEM SA
- 申请人地址： LU Luxembourg
- 专利权人： POLICHEM SA
- 当前专利权人： POLICHEM SA
- 当前专利权人地址： LU Luxembourg
- 代理机构： Hueschen and Sage
- 优先权： EP12167640 20120511
- 国际申请： PCT/EP2013/055078 WO 20130313
- 国际公布： WO2013/167295 WO 20131114
- 主分类号： C07D413/12
- IPC分类号： C07D413/12 ; A61K31/422 ; C07C241/02 ; C07D263/26
摘要：
(R)-Nifuratel is disclosed together with its use as bactericide and bacteriostatic agent as well as the pharmaceutical compositions containing the same; (R)-nifuratel has been surprisingly found to possess a better antimicrobial profile than either nifuratel racemate or (S)-nifuratel. A new procedure for the synthesis of both (R)-Nifuratel and (S)-Nifuratel is also disclosed.
公开/授权文献
信息查询
