发明授权
US09284416B2 Process for converting a solid (meth)acrylate copolymer into a dispersed form by means of a dispersing agent
有权
通过分散剂将固体(甲基)丙烯酸酯共聚物转化为分散形式的方法
- 专利标题: Process for converting a solid (meth)acrylate copolymer into a dispersed form by means of a dispersing agent
- 专利标题(中): 通过分散剂将固体(甲基)丙烯酸酯共聚物转化为分散形式的方法
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申请号: US13504527申请日: 2009-11-16
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公开(公告)号: US09284416B2公开(公告)日: 2016-03-15
- 发明人: Erna Roth , Ruediger Alexowsky , Hans-Ulrich Petereit , Kathrin Nollenberger , Christian Meier
- 申请人: Erna Roth , Ruediger Alexowsky , Hans-Ulrich Petereit , Kathrin Nollenberger , Christian Meier
- 申请人地址: DE Darmstadt
- 专利权人: Evonik Roehm GmbH
- 当前专利权人: Evonik Roehm GmbH
- 当前专利权人地址: DE Darmstadt
- 代理机构: Oblon, McClelland, Maier & Neustadt, L.L.P.
- 国际申请: PCT/EP2009/065244 WO 20091116
- 国际公布: WO2011/057676 WO 20110519
- 主分类号: A61K47/32
- IPC分类号: A61K47/32 ; C08K5/11 ; C08K5/1535 ; A61P11/00 ; C08K5/41 ; C09D105/00 ; A61K31/522 ; C08L5/00 ; C08K5/06 ; C08J3/03 ; A61K9/50 ; C08J3/05 ; A61K9/28
摘要:
The present invention provides a process for converting a solid (meth)acrylate copolymer into a dispersed form by preparing an aqueous dispersion comprising the components (a) a (meth)acrylate copolymer which is composed of free-radical polymerized methyl methacrylate, ethylacrylate and a salt of 2-trimethylammoniumethyl methacrylate, present in solid form as a powder or as a granulate, (b) up to 50% by weight calculated on the (meth)acrylate copolymer (a) of a dispersing agent selected from the groups of (b) i) plasticizers in combination with emulsifiers and/or (b) ii) pharmaceutically acceptable carbohydrates having 6 to 18 carbon atoms with a functional group and (c) water by mixing the components (a), (b) and (c) to give a suspension which becomes an aqueous dispersion during the conversion of the solid (meth)acrylate copolymer into the dispersed form, characterized in that, the (meth)acrylate copolymer is converted into the dispersed form by means of the presence of the dispersing agent at a temperature of less than 50° C.
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