Invention Grant
- Patent Title: Multicomponent crystalline system comprising deferasirox and isonicotinamide and a process for the preparation thereof
- Patent Title (中): 包含去铁罗糖和异烟酰胺的多组分结晶体及其制备方法
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Application No.: US14415875Application Date: 2013-08-05
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Publication No.: US09290452B2Publication Date: 2016-03-22
- Inventor: Andreas Hafner , Fritz Blatter , Eva Roedel , Martin Szelagiewicz , Tiziana Chiodo , Tobias Hintermann , Beate Salvador , Marcus Vossen
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P
- Priority: EP12179346 20120806
- International Application: PCT/EP2013/066360 WO 20130805
- International Announcement: WO2014/023682 WO 20140213
- Main IPC: C07D213/81
- IPC: C07D213/81 ; C07D249/08

Abstract:
The present invention refers to a multicomponent crystalline system (co-crystal) comprising a compound of formula (1) (4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; INN: Deferasirox) formula (1) and a compound of formula (2) (Isonicotinamide; pyridine-4-carboxamide) formula (2), as well as to a process for obtaining the same.
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