Invention Grant
US09290458B2 Amorphous form of an AKT inhibiting pyrimidinyl-cyclopentane compound, compositions and methods thereof
有权
AKT抑制嘧啶基 - 环戊烷化合物的无定形形式，其组合物和方法
- Patent Title: Amorphous form of an AKT inhibiting pyrimidinyl-cyclopentane compound, compositions and methods thereof
- Patent Title (中): AKT抑制嘧啶基 - 环戊烷化合物的无定形形式，其组合物和方法
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Application No.: US14401092Application Date: 2013-05-17
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Publication No.: US09290458B2Publication Date: 2016-03-22
- Inventor: Paroma Chakravarty , Sanjeev Kothari , Francis Gosselin , Scott J. Savage , Jeffrey Stults
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- International Application: PCT/US2013/041728 WO 20130517
- International Announcement: WO2013/173811 WO 20131121
- Main IPC: C07D239/70
- IPC: C07D239/70 ; A61K31/496 ; C07D403/04 ; A61K31/517
Abstract:
Disclosed is (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one monohydrochloride, forms, formulations, pharmaceutical compositions, processes of manufacturing and methods of use thereof.
Public/Granted literature
- US20150274677A1 AMORPHOUS FORM OF AN AKT INHIBITING PYRIMIDINYL-CYCLOPENTANE COMPOUND, COMPOSITIONS AND METHODS THEREOF Public/Granted day:2015-10-01
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