Invention Grant
US09290573B2 Therapeutic low density lipoprotein-related protein 6 (LRP6) multivalent antibodies
有权
治疗性低密度脂蛋白相关蛋白6（LRP6）多价抗体
- Patent Title: Therapeutic low density lipoprotein-related protein 6 (LRP6) multivalent antibodies
- Patent Title (中): 治疗性低密度脂蛋白相关蛋白6（LRP6）多价抗体
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Application No.: US13696372Application Date: 2011-05-05
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Publication No.: US09290573B2Publication Date: 2016-03-22
- Inventor: Feng Cong , Seth Ettenberg , David Jenkins , Ming Lei , Andreas Loew , Karen Vincent , Li Zhou
- Applicant: Feng Cong , Seth Ettenberg , David Jenkins , Ming Lei , Andreas Loew , Karen Vincent , Li Zhou
- Applicant Address: CH BASEL
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH BASEL
- Agent John Prince
- International Application: PCT/EP2011/057200 WO 20110505
- International Announcement: WO2011/138391 WO 20111110
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/46 ; A61K39/395 ; A61K39/00
Abstract:
The present disclosure relates to an antibody or antigen binding fragment having at least two receptor binding domains for two different binding sites of LRP6 and compositions and methods of use thereof.
Public/Granted literature
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