发明授权
- 专利标题： MO-1 conditional knock-out non-human animal and uses thereof
- 专利标题（中）： MO-1条件敲除非人类动物及其用途
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申请号： US13508399申请日： 2010-11-08
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公开(公告)号： US09295239B2公开(公告)日： 2016-03-29
- 发明人: Zvi Borochowitz
- 申请人： Zvi Borochowitz
- 申请人地址： IL Haifa
- 专利权人： Medical Research & Development Fund for Health Services Bnai Zion Medical Center, THE STATE OF ISRAEL
- 当前专利权人： Medical Research & Development Fund for Health Services Bnai Zion Medical Center, THE STATE OF ISRAEL
- 当前专利权人地址： IL Haifa
- 优先权： IL201999 20091108
- 国际申请： PCT/IL2010/000920 WO 20101108
- 国际公布： WO2011/055366 WO 20110512
- 主分类号： A01K67/00
- IPC分类号： A01K67/00 ; C12N15/00 ; A01K67/027 ; C12N15/85
摘要：
A conditional knock-out non-human animal is disclosed. Wherein some cells of the non-human animal but not all the cells comprise a disrupted MO-1 nucleic acid sequence, wherein the disruption results in an inability of the non-human animal to produce detectable levels of the MO-1 protein, as assayed by Southern blot analysis.
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