Invention Grant
- Patent Title: Bromodomain inhibitors
- Patent Title (中): 溴代抑制剂
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Application No.: US13828285Application Date: 2013-03-14
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Publication No.: US09296741B2Publication Date: 2016-03-29
- Inventor: Le Wang , John K Pratt , Keith F McDaniel , Yujia Dai , Steven D Fidanze , Lisa Hasvold , James H Holms , Warren M Kati , Dachun Liu , Robert A Mantei , William J McClellan , George S Sheppard , Carol K Wada
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agent Glen J. Gesicki
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D487/04 ; A61K31/437 ; A61K31/5377 ; A61K31/541 ; A61K31/5025 ; A61K45/06

Abstract:
The present invention provides for compounds of formula (I) wherein A1, A2, A3, A4, X1, X2, Y1, L1, G1, Rx, and Ry have any of the values defined thereof in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Public/Granted literature
- US20140162971A1 BROMODOMAIN INHIBITORS Public/Granted day:2014-06-12
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