发明授权
- 专利标题: Compositions and methods of use for antibodies of Dickkopf-1
- 专利标题(中): Dickkopf-1抗体的组合物和使用方法
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申请号: US14178892申请日: 2014-02-12
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公开(公告)号: US09296813B2公开(公告)日: 2016-03-29
- 发明人: Janine R. Shulok , Feng Cong , Mark C. Fishman , Seth Ettenberg , Michael Bardroff , Mariel Donzeau , Stefanie Urlinger
- 申请人: Janine R. Shulok , Feng Cong , Mark C. Fishman , Seth Ettenberg , Michael Bardroff , Mariel Donzeau , Stefanie Urlinger
- 申请人地址: CH Basel
- 专利权人: NOVARTIS AG
- 当前专利权人: NOVARTIS AG
- 当前专利权人地址: CH Basel
- 代理商 John Prince
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/22 ; C07K16/18 ; A61K31/675 ; A61K45/06 ; A61K39/00
摘要:
Antibodies and fragments that bind to the protein target Dickkopf (DKK1) are provided, as are methods of use and kits, for treating a target cell, in particular, a cell associated with an osteolytic condition.
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