A method and device for driving a digital speaker based on code conversion are provided in the invention. The method comprises the steps of: (1) converting input format; (2) performing multi-bit Σ-Δ modulation; (3) thermometer code conversion; (4) dynamic mismatch-shaping processing; (5) pulse width modulation code conversion; and (6) controlling on/off status switching of the MOSFET of a full-bridge power amplification network to drive a digital speaker load sound. The device comprises a sound source, an input format converter, a multi-bit Σ-Δ modulator, a thermometer coder, a dynamic mismatch shaper, a code converter, a multi-channel digital amplifier and a digital speaker load which are connected to each other in sequence. By means of the device and method of the invention, the switching rate of the power tube, the power dissipation and heating generated during the switching are reduced, the sound quality and efficiency of electroacoustic restoration are improved, the volume, weight and implementation cost of the system are decreased, and the level of electromagnetic radiation is reduced. Furthermore, the device and method of the invention also have excellent immunity to the frequency response deviation of multiple digital channels.