Invention Grant
- Patent Title: Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
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Application No.: US14582144Application Date: 2014-12-23
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Publication No.: US09303025B2Publication Date: 2016-04-05
- Inventor: Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura Hexamer , Aaron R. Kunzer , Robert A. Mantei , Cheol-Min Park , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Jones Day
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D405/14 ; C07D413/12 ; C07D417/12 ; C07D209/08 ; C07D211/58 ; C07D213/74 ; C07D213/84 ; C07D231/56 ; C07D235/06 ; C07D277/24 ; C07D295/30 ; C07D309/04 ; C07D471/04 ; C07D309/08

Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Public/Granted literature
- US20150183775A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES Public/Granted day:2015-07-02
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