Invention Grant
- Patent Title: Substituted piperazines as AKT inhibitors
- Patent Title (中): 取代的哌嗪作为AKT抑制剂
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Application No.: US12307526Application Date: 2007-07-05
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Publication No.: US09303040B2Publication Date: 2016-04-05
- Inventor: Ian S. Mitchell , James F. Blake , Rui Xu , Nicholas C. Kallan , Dengming Xiao , Keith Lee Spencer , Josef R. Bencsik
- Applicant: Ian S. Mitchell , James F. Blake , Rui Xu , Nicholas C. Kallan , Dengming Xiao , Keith Lee Spencer , Josef R. Bencsik
- Applicant Address: US CO Boulder
- Assignee: ARRAY BIOPHARMA INC.
- Current Assignee: ARRAY BIOPHARMA INC.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- International Application: PCT/US2007/072884 WO 20070705
- International Announcement: WO2008/006039 WO 20080110
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D409/02 ; C07D495/04
Abstract:
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US20120329808A1 DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS Public/Granted day:2012-12-27
Information query
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