Systems and methods are disclosed for identifying image capture instructions for capturing images that may be used to generate quality depth maps. In some examples, the image capture instructions are generated by predictively determining in a scene-independent manner configuration settings to be used by a camera to capture a minimal quantity of images for generating the quality depth map. The image capture instructions may thus indicate a quantity of images to be captured and the aperture and focus settings to be used when capturing the images. The image capture instructions may be determined based in part on a distance estimate, camera calibration information and a predetermined range of optimal blur radii. The range of optimal blur radii ensures that there will be sufficient depth information for generating a depth map of a particular quality from the yet-to-be-captured images.