发明授权
US09309224B2 N-acyl-N′-(pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activities
有权
N-酰基-N' - （吡啶-2-基）脲和表现出抗癌和抗增殖活性的类似物
- 专利标题： N-acyl-N′-(pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activities
- 专利标题（中）： N-酰基-N' - （吡啶-2-基）脲和表现出抗癌和抗增殖活性的类似物
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申请号： US14214179申请日： 2014-03-14
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公开(公告)号： US09309224B2公开(公告)日： 2016-04-12
- 发明人: Daniel L. Flynn , Timothy Malcolm Caldwell , Thiwanka Samarakoon , Lakshminarayana Vogeti , Michael D. Kaufman , William C. Patt , YuMi Ahn
- 申请人： Deciphera Pharmaceuticals, LLC
- 申请人地址： US KS Lawrence
- 专利权人： Deciphera Pharmaceuticals, LLC.
- 当前专利权人： Deciphera Pharmaceuticals, LLC.
- 当前专利权人地址： US KS Lawrence
- 代理机构： Cooley LLP
- 主分类号： C07D213/65
- IPC分类号： C07D213/65 ; C07D401/14 ; C07D401/12 ; C07D405/14 ; C07D493/08
摘要：
Described are compounds of Formula 1 which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.
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