Invention Grant
- Patent Title: Polypeptides, nucleic acids and uses thereof
- Patent Title (中): 多肽，核酸及其用途
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Application No.: US14496600Application Date: 2014-09-25
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Publication No.: US09309314B2Publication Date: 2016-04-12
- Inventor: Bruno Reversade
- Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR)
- Applicant Address: SG Singapore
- Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR)
- Current Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR)
- Current Assignee Address: SG Singapore
- Agency: Nixon Peabody LLP
- Agent Mark J. FitzGerald
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07K16/26 ; G01N33/74 ; C07K14/575 ; C07K7/00
Abstract:
We describe an ELABELA polypeptide comprising a sequence CXXXRCXXXHSRVPFP (SEQ ID NO: 1), in which X signifies an amino acid residue, such as a sequence selected from the group consisting of: SEQ ID NO: 2 to SEQ ID NO: 18, preferably CLQRRCMPLHSRVPFP (SEQ ID NO: 2), or a fragment, homolog, variant or derivative thereof, which polypeptide is capable of maintaining self-renewal and/or pluripotency of a stem cell.
Public/Granted literature
- US20150153365A1 POLYPEPTIDES, NUCLEIC ACIDS AND USES THEREOF Public/Granted day:2015-06-04
Information query
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