A new process of manufacturing a hybrid cannula may include creating a first part with at least two components, overmolding at least two components of a second part to a channel in each component of the first part, and fixing the components of the first part together. The second part may include various types of features such as thick/thin dams, squirt membranes, and/or duck bill dams inside the hybrid cannula. Each dam may have any number, shape, orientation, and length of slits/openings. The slits/openings may allow passage of an instrument while the dam(s) may prevent fluid from passing through the hybrid cannula. A third part may optionally be overmolded to at least a portion of the first part, at least a portion of the second part, or both. The third part may provide an extension, a flange, or a combination thereof at a distal end of the hybrid cannula.