Technology for reducing interference in collocated radios is disclosed. One method comprises identifying a repeating transmit/receive (Tx/Rx) pattern for multiple radios located in a mobile communication device having a Bluetooth radio collocated with an OFDMA radio. A persistent reservation is requested for at least one sub-frame from the OFDMA radio when the repeating Tx/Rx pattern indicates a Bluetooth packet wherein the Bluetooth radio can not transmit without interference with the OFDMA radio. The repeating Tx/Rx pattern is modified based on the persistent reservation. The Bluetooth radio can communicate based on the modified repeating Tx/Rx pattern to enable interference free communication for the Bluetooth radio and the OFDMA radio in the multi-radio mobile communication device. A collocated WiFi radio's transceiver can align its Tx/Rx with the Tx/Rx pattern, and transmit and receive at the same time slots that other collocated radios are transmitting, and receiving.