Scheduled clear to send (CTS) for multiple user, multiple access, and/or MIMO wireless communications. Before sending transmissions, a request to send (RTS)/clear to send (CTS) exchange takes place between a transmitting wireless communication device and multiple receiving wireless communication devices may take place therein. The transmitting wireless communication device (e.g., an AP) may generate and transmit a multi-user request to send (mRTS) frame to a number of receiving wireless communication devices (e.g., STAs). The mRTS frame can include information and instructions therein to direct the manner by which all or a subset of the receiving wireless communication devices are to provide CTS responses back to the transmitting wireless communication device. The mRTS frame may be an OFDMA frame, a MU-MIMO frame, or a combination thereof. The CTS responses may be received in accordance with any one or combination of OFDM signaling, OFDMA signaling, and MU-MIMO signaling.