- 专利标题： Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
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申请号： US14451879申请日： 2014-08-05
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公开(公告)号： US09339467B2公开(公告)日： 2016-05-17
- 发明人: Ronald A. Beyerinck , Heather L. M. Deibele , Dan E. Dobry , Roderick J. Ray , Dana M. Settell , Ken R. Spence
- 申请人： Bend Research, Inc.
- 申请人地址： US OR Bend
- 专利权人： Bend Research, Inc.
- 当前专利权人： Bend Research, Inc.
- 当前专利权人地址： US OR Bend
- 代理机构： Klarquist Sparkman, LLP
- 主分类号： A61K9/16
- IPC分类号： A61K9/16 ; B01J2/04 ; A61K31/404 ; A61K31/47 ; A61J3/02 ; A61K9/14
摘要：
Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
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