Invention Grant
- Patent Title: Fusion protein comprising the extracellular domain of a filovirus glycoprotein fused to an immunoglobulin heavy chain constant region
- Patent Title (中): 融合蛋白包含与免疫球蛋白重链恒定区融合的病毒糖蛋白的细胞外结构域
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Application No.: US13882041Application Date: 2011-10-28
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Publication No.: US09347951B2Publication Date: 2016-05-24
- Inventor: Gerardo Kaplan , Krishnamurthy Konduru , Jerome Jacques , Sina Bavari , Steven Bradfute
- Applicant: Gerardo Kaplan , Krishnamurthy Konduru , Jerome Jacques , Sina Bavari , Steven Bradfute
- Applicant Address: US DC Washington
- Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH
- Current Assignee: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH
- Current Assignee Address: US DC Washington
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2011/058418 WO 20111028
- International Announcement: WO2012/154203 WO 20121115
- Main IPC: G01N33/68
- IPC: G01N33/68 ; A61K39/12 ; G01N33/569 ; C07K14/005 ; A61K39/00
Abstract:
This invention provides fusion proteins comprising a Filovirus glycoprotein segment and an immunoglobulin polypeptide segment. The fusion proteins are useful in immunogenic compositions to protect against infections by Filoviruses, such as Ebola virus, in both humans and non-human animals. The fusion proteins are also useful in diagnostic assays to detect Filovirus infections.
Public/Granted literature
- US20130323243A1 FILOVIRUS FUSION PROTEINS AND THEIR USES Public/Granted day:2013-12-05
Information query
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