A computer-implemented method and apparatus are described for automatically selecting a region in a blurred image for blur kernel estimation. The method may include accessing a blurred image and defining a size for each of a plurality of regions in the image. Thereafter, metrics for at least two of the plurality of regions are determined, wherein the metrics are based on a number of edge orientations within each region. A region is selected from the plurality of regions based on the determined metrics, and a blur kernel for deblurring the blurred image is then estimated for the selected region. The blurred image is then deblurred using the blur kernel.