Invention Grant
- Patent Title: Cyclic amine substituted heterocyclic CETP inhibitors
- Patent Title (中): 环胺取代的杂环CETP抑制剂
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Application No.: US14398165Application Date: 2013-04-26
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Publication No.: US09353101B2Publication Date: 2016-05-31
- Inventor: John J. Acton, III , Feng Ye , Petr Vachal , Deyou Sha , James F. Dropinski , Lin Chu , Debra Ondeyka , Alexander J. Kim , Vincent J. Colandrea , Yi Zang , Fengqi Zhang , Guizhen Dong
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Anna L. Cocuzzo
- International Application: PCT/US2013/038498 WO 20130426
- International Announcement: WO2013/165854 WO 20131107
- Main IPC: C07D417/14
- IPC: C07D417/14 ; C07D413/14 ; A61K31/506 ; A61K31/5377 ; A61K31/444 ; A61K45/06
Abstract:
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and may be useful for raising HDL-cholesterol and reducing LDL-cholesterol in human patients and for treating or preventing atherosclerosis.
Public/Granted literature
- US20150111866A1 CYCLIC AMINE SUBSTITUTED HETEROCYCLIC CETP INHIBITORS Public/Granted day:2015-04-23
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