An automatic detection method of an arrangement of a video wall including a plurality of monitors and a video wall system are provided. The method includes: calling, by a control computer, identification information of a first monitor of the plurality of monitors; sending, by the first monitor, a response signal to the control computer and sending, by a second monitor which does not correspond to the called identification information, a detecting signal including a received direction of the response signal to the control computer; and receiving, by the control computer, the detecting signal, and determining the arrangement of the plurality of monitors according to the received detecting signal.