Invention Grant
US09359376B2 Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds
有权
取代的甲基甲酰基试剂及其使用方法来改变化合物的物理化学和/或药代动力学性质
- Patent Title: Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds
- Patent Title (中): 取代的甲基甲酰基试剂及其使用方法来改变化合物的物理化学和/或药代动力学性质
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Application No.: US14110373Application Date: 2012-04-09
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Publication No.: US09359376B2Publication Date: 2016-06-07
- Inventor: Sundeep Dugar , Dinesh Mahajan , Frank Peter Hollinger
- Applicant: Sundeep Dugar , Dinesh Mahajan , Frank Peter Hollinger
- Applicant Address: SG Singapore
- Assignee: SPHAERA PHARMA PTE. LTD
- Current Assignee: SPHAERA PHARMA PTE. LTD
- Current Assignee Address: SG Singapore
- Agency: Foley & Lardner LLP
- Priority: IN1024/DEL/2011 20110408
- International Application: PCT/IN2012/000248 WO 20120409
- International Announcement: WO2012/137225 WO 20121011
- Main IPC: C07D307/77
- IPC: C07D307/77 ; C07D305/00 ; C07D413/00 ; C07D405/00 ; C07D495/14 ; C07D401/14 ; C07D405/14 ; C07D213/80 ; C07D213/81 ; C07D213/82 ; C07D401/04 ; C07D401/12 ; C07D405/12 ; C07D471/04 ; C07D487/04 ; C07D487/22 ; C07D491/22 ; C07D295/20 ; C07D305/14 ; C07D213/803 ; C07D491/147
Abstract:
The present invention relates to the synthesis and application of novel chiral/achiral substituted methyl formyl reagents to modify pharmaceutical agents and/or biologically active substances to modify the physicochemical, biological and/or pharmacokinetic properties of the resulting compounds from the unmodified original agent.
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