Techniques are provided for reducing interference in a wireless network. A user equipment device in a first wireless coverage area of a wireless network using a time division duplex transmission scheme to designate a maximum timing advance value for uplink transmissions based on potential interference between uplink transmissions made by the user equipment device in the first wireless coverage area or at least one other user equipment device in the first wireless coverage area, and downlink transmissions intended for at least one user equipment device in a second wireless coverage area of the wireless network. The maximum timing advance value may be based on relative cell radii or other cell properties of the first and second wireless coverage areas. A base station may determine the maximum timing advance and transmit the maximum timing advance to the user equipment device.