Invention Grant
- Patent Title: Process for producing solid particles
- Patent Title (中): 生产固体颗粒的方法
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Application No.: US14430956Application Date: 2013-09-25
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Publication No.: US09364438B2Publication Date: 2016-06-14
- Inventor: Naoyuki Murata , Shigeo Yanai
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2012-212264 20120926
- International Application: PCT/JP2013/075948 WO 20130925
- International Announcement: WO2014/050910 WO 20140403
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K31/18 ; A61K31/24 ; A61K9/16
Abstract:
A method of producing crystal of a poorly water-soluble pharmaceutical compound, including mixing a solution of a poorly water-soluble pharmaceutical compound in a good solvent and nanobubble water or an aqueous nanobubble solution to precipitate crystal of the poorly water-soluble pharmaceutical compound. The crystal of a poorly water-soluble pharmaceutical compound obtained by the method is microparticulate and has more uniform particle size distribution, and is superior in the absorbability and sustainability.
Public/Granted literature
- US20150250728A1 PROCESS FOR PRODUCING SOLID PARTICLES Public/Granted day:2015-09-10
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