Invention Grant
US09364482B2 Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
有权
取代的苯并呋喃化合物及其用于治疗病毒性疾病的方法
- Patent Title: Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
- Patent Title (中): 取代的苯并呋喃化合物及其用于治疗病毒性疾病的方法
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Application No.: US14898768Application Date: 2014-06-19
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Publication No.: US09364482B2Publication Date: 2016-06-14
- Inventor: Xing Dai , Hong Liu , Anandan Palani , Shuwen He , Ravi Nargund , Dong Xiao , Nicolas Zorn , Qun Dang , Casey C. McComas , Xuanjia Peng , Peng Li , Richard Soll
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Alysia A. Finnegan; Gloria Fuentes
- Priority: WOPCT/CN2013/000746 20130624
- International Application: PCT/US2014/043072 WO 20140619
- International Announcement: WO2014/209727 WO 20141231
- Main IPC: A61K31/65
- IPC: A61K31/65 ; A61K31/519 ; A61K31/517 ; A61K31/437 ; A61K31/4725 ; A61K31/06 ; C07D498/04 ; C07D471/04 ; C07D405/04 ; C07D475/02 ; C07D405/14 ; A61K31/5365 ; A61K31/53 ; A61K45/06
Abstract:
The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system. (I)
Public/Granted literature
- US20160136172A1 SUBSTITUTED BENZOFURAN COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES Public/Granted day:2016-05-19
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