发明授权
US09365584B2 Thieno [2,3-B] pyridinedione activators of AMPK and therapeutic uses thereof
有权
噻吩并[2,3-B]吡啶二酮激活剂及其治疗用途
![Thieno [2,3-B] pyridinedione activators of AMPK and therapeutic uses thereof](/docs/US/2016-06-14/US09365584B2/abs.jpg.600x600.jpg)
- 专利标题： Thieno [2,3-B] pyridinedione activators of AMPK and therapeutic uses thereof
- 专利标题（中）： 噻吩并[2,3-B]吡啶二酮激活剂及其治疗用途
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申请号： US13519407申请日： 2010-12-28
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公开(公告)号： US09365584B2公开(公告)日： 2016-06-14
- 发明人: Daniel Cravo , Sophie Hallakou-Bozec , Sébastien Bolze , Franck Lepifre , Laurent Faveriel , Jean-Denis Durand , Christine Charon
- 申请人： Daniel Cravo , Sophie Hallakou-Bozec , Sébastien Bolze , Franck Lepifre , Laurent Faveriel , Jean-Denis Durand , Christine Charon
- 申请人地址： FR Lyons
- 专利权人： Poxel
- 当前专利权人： Poxel
- 当前专利权人地址： FR Lyons
- 代理机构： McDonnell Boehnen Hulbert & Berghoff
- 优先权： EP09306344 20091229
- 国际申请： PCT/EP2010/070811 WO 20101228
- 国际公布： WO2011/080277 WO 20110707
- 主分类号： C07D495/04
- IPC分类号： C07D495/04
![Thieno [2,3-B] pyridinedione activators of AMPK and therapeutic uses thereof](/abs-image/US/2016/06/14/US09365584B2/abs.jpg.150x150.jpg)
摘要：
The invention relates to compounds that are direct activators of AMPK (AMP-activated protein kinase) and their use in the treatment of disorders regulated by activation of AMPK. For instance, compounds according to the invention are useful for the treatment of diabetes, metabolic syndrome, obesity, inflammation, cancer and cardiovascular diseases.
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